Frey syndrome is characterized by unilateral flushing and sweating of the facial skin innervated by the auriculotemporal nerve (neck, parotid region, and. A neurologist from Poland, Dr. Lucja Frey, provided a detailed assessment of the disorder and coined the term “auriculotemporal syndrome” in Auriculotemporal nerve syndrome, also known as Frey syndrome, is an uncommon clinical entity in children. It is widely thought to be the result.

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Historically, surgical treatment of Frey syndrome has not been used. The most widely held theory is that Frey syndrome results from simultaneous damage to sympathetic and parasympathetic nerves in the region of the face or neck near the parotid glands.

The auriculotemporal nerve supplies nerves innervates aurichlotemporal certain structures in the face including the parotid glands. In older reports, infections of the parotid glands were suspected, but a detailed examination always points to a surgical drainage of a parotid abscess.

In contrast to food allergy, Frey syndrome is usually unilateral, with a segmental distribution in the areas innervated by the auriculotemporal nerve. Arch Facial Plast Surg. Salivary gland pathology Diabetes Syndromes affecting the nervous system Rare auriculotempofal.

Frey syndrome auriiculotemporal males and females in equal numbers.

Reports in the literature have supported that the use of an SCM muscle flap decreases the incidence of Frey syndrome. The exact incidence of Frey syndrome is unknown. Sternocleidomastoid muscle flap Syndrom sternocleidomastoid SCM muscles flap is a muscular flap with a tripartite blood supply.

In some patients, symptoms may be mild and affected individuals may not be bothered by the symptoms. Additional symptoms that may be associated with Frey syndrome include flushing and warmth in the affected areas.


The percentage of individuals who develop Frey syndrome after a parotidectomy is controversial and reported estimates range from percent.

A An anatomic drawing of the superficial temporal artery and vein supplying the superficial temporal fascia demonstrating the proximity to the temporal branch of the facial nerve.

Create a free personal account to access your subscriptions, sign up for alerts, and more. Periapical, mandibular and maxillary hard tissues — Bones of jaws Agnathia Alveolar osteitis Buccal exostosis Cherubism Idiopathic osteosclerosis Mandibular fracture Microgenia Micrognathia Intraosseous cysts Odontogenic: The characteristic symptom of Frey syndrome is gustatory sweating, which is excessive sweating on the cheek, forehead, and around the ears shortly after eating certain foods, specifically foods that produce a strong salivary response such as sour, spicy or salty foods.

Since its development, it has been used in parotidectomy for the prevention of Frey syndrome.

Auriculotemporal Syndrome (Frey Syndrome)

Open in a separate window. Box Bethesda, MD Phone: Increased Skin Flap Thickness Within the facial skin, the sweat glands are positioned at the same level or slightly deeper than the base of the hair follicles. Purchase syndeome Subscribe now. The response may last for a period of 6 months and the treatment can be repeated.

National Institutes of Health. Given the limited number of studies on transposition procedures, no recommendations can be made on its evidence-based efficacy.

Auriculotemporal nerve syndrome / Frey syndrome/Gustatory sweating

Singleton G, Cassisi N. Repeated botulinum toxin auriculotemporl A injections to treat patients with Frey syndrome. Therefore, the parasympathetic nerves that normally tell the parotid glands to produce saliva in response to tasting food now respond by instructing the sweat glands to produce sweat and the blood vessels to widen dilate.

An unusual variant presenting as gustatory flushing mimicking food allergy”.

Treatment is syndrlme and directed toward relief of symptoms. A neurologist from Poland, Dr. Between attacks of pain there is sometimes numbness or other altered sensations anesthesia or paresthesia. Frey syndrome is a common sequela of parotidectomy, and although it is not frequently manifested clinically, it can cause significant morbidity for those affected.


Rare Disease Database

Normally, damaged nerve fiber s eventually heal themselves regenerate. New England Journal of Medicine. Nasopalatine duct Median mandibular Median palatal Traumatic bone Osteoma Osteomyelitis Osteonecrosis Bisphosphonate-associated Neuralgia-inducing cavitational osteonecrosis Osteoradionecrosis Osteoporotic bone marrow defect Paget’s disease of bone Periapical abscess Phoenix abscess Periapical periodontitis Stafne defect Torus mandibularis.

Until recently, most treatment measures have generally been unsatisfactory. Frey syndrome may occur in association with several neurologic disorders, such as syringomyelia, central nervous system tumors, and epilepsy.

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Retrieved from ” https: The use of a TPFF was first described in a series of 7 patients undergoing parotidectomy for the prevention of Frey syndrome in by Sultan and colleagues. The temporoparietal fascia flap TPFF is a broad, vascularized fascia flap that is based off the superficial temporal artery Fig. Get free access to newly published articles. From Arad A, Blitzer A.

Auriculotemporal Syndrome (Frey Syndrome)

Information on current clinical trials is posted on the Internet at www. Of note, local reconstruction with the above techniques is not advised in the presence of malignant disease or gross spillage of benign tumors due to the concern for local recurrence. The starch turns blue on exposure to iodine in the presence of sweat.