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Severe hypoglycemia requiring medical intervention in a large cohort of adults with diabetes receiving care in U. Insulin-dependent glucose uptake by skeletal muscles is reduced due to suppression of insulin receptors and glucose transporter GLUT-4 [ 5 ].

It also has a beneficial effect on lipid profile. Get to Know Us. Molecular and Biomolecular SpectroscopyA. It should be characterised by a gentle start and gentle finish, without flexing exercises. During this period the number of people aged over 80 years living in Poland has doubled.

The basis of treating an elderly person is trying to improve or at least maintain their current quality of life. Frailty syndrome Frailty syndrome in geriatrics means that an organism lacks the ability to maintain the homeostasis and react to stress properly. Hypoglycemic episodes and risk of dementia in older patients with type 2 diabetes mellitus. Comparison of the prognostic importance of diagnosed diabetes, co-morbidity and frailty in older people. Alexa Actionable Analytics for the Web.

Therapy should start with small doses, e. Excess mortality among persons with type 2 diabetes. Because the number of people with diabetes is still growing, preventative actions have been evaluated.

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Additionally, elderly people have an impaired thirst mechanism, which increases the risk of dehydration. It leads to loss of body mass, sarcopaenia, undernutrition, tiredness, lack of physical activity, and as a consequence to increased risk of falling, developing disability, dependence on other people, hospitalisation, and death.

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Loss of body mass connected with age and frailty syndrome can result in a relevant decrease in the demand for anti-diabetic medications, both orally administered and insulin.

Amazon Advertising Find, attract, and engage customers. If possible, it is worth starting the treatment from preparations of the lowest risk of hypoglycaemia, which means from basal insulin NPH or long-lasting analogue.

Among adults of all ages, elderly people have the highest risk of hypoglycaemia as a complication of diabetes treatment [ 20 ]. AmazonGlobal Ship Orders Internationally.

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Cortisol, as a catabolic hormone, is responsible for proteolysis, and its higher level leads to reduced muscle mass. During treatment, it is necessary to consider a higher number of side effects of medications and drug interactions due to polypragmasia.

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November 10, Label: There’s a problem loading this menu right now. Old age is connected with numerous health problems.

Nevertheless, the influence of these drugs on reducing body mass — which is a desirable effect biekanski most patients with type 2 diabetes — in elderly people may increase sarcopaenia and risk of falling as well as undernutrition. These problems show that a necessary factor in proper diabetes therapy, also in advanced age, is systematic blood glucose self-monitoring. Thus, it is not the best therapeutic option for seniors.


Reduced physical activity of elderly people escalates this process. Flozins inhibit re-uptake of glucose in renal proximal tubule, resulting in an increase in glucose excretion in urine.

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The most important goal for the elderly is to improve or at least maintain their current quality of life. Is hyperglycemia associated with frailty status in older women?

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Losing weight connected with frailty syndrome may significantly decrease demand for antihypertensive drugs and increase the risk of orthostatic hypotension and falling. According to ACCORD research, intensive treatment of diabetes increases the risk of death in patients with a high cardiovascular risk. Symptoms of hyperglycaemia should be reduced gradually avoiding hypoglycaemia at the same time.

Hypoglycemia unawareness in older compared with middle-aged patients with bielansoi 2 diabetes. Regular physical effort is beneficial to prevent sarcopaenia bielansk obesity and improves insulin sensitivity.